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LEVITRA (VARDENAFIL): MEDICATION GUIDE

Read the Patient Information about Levitra before you start taking it and again each time you get a refill. There may be new information. You may also find it helpful to share this information with your partner. This leaflet does not take the place of talking with your doctor. You and your doctor should talk about Levitra (Vardenafil) when you start taking it and at regular checkups. If you do not understand the information, or have questions, talk with your doctor or pharmacist.

What important information should you know about Levitra (Vardenafil) tablets?

Levitra can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke.

Do not take Vardenafil Hydrochloride (Levitra) if you:

  • take any medicines called "nitrates".
  • use recreational drugs called "poppers" like amyl nitrate and butyl nitrate.

    Tell all your doctor, pharmacist, or other healthcare professional that you take Levitra. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took Levitra.


    What is Vardenafil Hydrochloride (Levitra) tablets?

    Levitra is a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men. ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him. LEVITRA may help a man with ED get and keep an erection when he is sexually excited.

    Levitra (Vardenafil HCl) does not:

  • cure ED
  • increase a man's sexual desire
  • protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your doctor about ways to guard against sexually transmitted diseases.
  • serve as a male form of birth control

    Levitra is only for men with ED. This medication is not for women or children. Levitra (Vardenafil HCl) tablets must be used only under a doctor's care.


    How does Levitra work?

    When a man is sexually stimulated, his body's normal physical response is to increase blood flow to his penis. This results in an erection. Vardenafil (Levitra) helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity. Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.


    Who can take Levitra?

    Talk to your physician to decide if this drug is right for you.

    Vardenafil (Levitra) tablets have been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes or who have undergone prostatectomy.


    Who should not take Levitra?

    Do not take this medicine if you:

  • take any medicines called "nitrates". Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.

    Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called "poppers" also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use Levitra (Vardenafil Hydrochloride) if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates.
  • you have been told by your healthcare provider to not have sexual activity because of health problems. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.
  • are allergic to Levitra or any of its ingredients. The active ingredient in Levitra is called vardenafil. See the end of this leaflet for a complete list of ingredients.


    What should you discuss with your doctor before taking Levitra (Vardenafil Hydrochloride) tablets?

    Before taking this medication, tell your doctor about all your medical problems, including if you:

  • have low blood pressure or have high blood pressure that is not controlled
  • have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor or pharmacist if it is safe for you to have sexual activity.
  • have had a stroke
  • have had a seizure
  • or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome)
  • have kidney problems and require dialysis
  • have liver problems
  • have retinitis pigmentosa, a rare genetic (runs in families) eye disease
  • have stomach ulcers
  • have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION)
  • have a bleeding problem
  • have had an erection that lasted more than 4 hours
  • have a deformed penis shape or Peyronie's disease
  • have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia


    Can other medications affect Levitra?

    Tell your doctor, pharmacist, or other healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Vardenafil HCl (Levitra) and other medicines may affect each other. Always check with your healthcare provider before starting or stopping any medicines. Especially tell your doctor if you take any of the following:

  • medicines called alpha-blockers. These include Hytrin (Terazosin HCl), Flomax (Tamsulosin HCl), Cardura (Doxazosin Mesylate), Minipress (Prazosin HCl) or Uroxatral (Alfuzosin HCl). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients the use of PDE5 inhibitor drugs, including Levitra, with alpha-blockers can lower blood pressure significantly leading to fainting. You should contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider.
  • medicines called nitrates
  • Ritonavir (Norvir) or Indinavir Sulfate (Crixivan), Saquinavir (Fortavase or Invirase) or Atazanavir (Reyataz)
  • medicines that treat abnormal heartbeat. These include quinidine, procainamide, amiodarone and sotalol.
  • Ketoconazole or Itraconazole (such as Nizoral or Sporanox)
  • Erythromycin or Clarithromycin
  • other medicines or treatments for ED


    How should you take Vardenafil HCl (Levitra) tablets?

    Take Levitra exactly as your doctor prescribes. This drug comes in different doses (2.5 mg, 5 mg, 10 mg, and 20 mg). For most men, the recommended starting dose is 10 mg. Take Levitra (Vardenafil) no more than once a day. Doses should be taken at least 24 hours apart. Some men can only take a low dose of Levitra because of medical conditions or medicines they take. Your doctor will prescribe the dose that is right for you.

  • If you are older than 65 or have liver problems, your doctor may start you on a lower dose of Levitra (Vardenafil) tablets.
  • If you have prostate problems or high blood pressure, for which you take medicines called alpha-blockers, your doctor may start you on a lower dose of Levitra.
  • If you are taking certain other medicines your doctor may prescribe a lower starting dose and limit you to one dose of Vardenafil Hydrochloride (Levitra) in a 72-hour (3 days) period.

    Take 1 Levitra tablet about 1 hour (60 minutes) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with Levitra. This medicine may be taken with or without meals.

    Do not change your dose of Vardenafil Hydrochloride (Levitra) tablets without talking to your physician. Your doctor may lower your dose or raise your dose, depending on how your body reacts to Levitra. If you take too much of this medication, call your healthcare professional or emergency room right away.


    What are the possible side effects of Levitra?

    The most common side effects with Levitra (Vardenafil HCl) are flushing, headache, stuffy or runny nose, indigestion, upset stomach, or dizziness. These side effects usually go away after a few hours. Call your doctor if you get a side effect that bothers you or one that will not go away.

    Levitra may uncommonly cause:

  • an erection that won't go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis including the inability to have erections.
  • color vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green. In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including Levitra (Vardenafil HCl) tablets) reported a sudden decrease or loss of vision in one or both eyes. It is not possible to determine whether these events are related directly to these medicines, to other factors such as high blood pressure or diabetes, or to a combination of these. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including Levitra, and call a doctor right away.

    Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including Vardenafil (Levitra). It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking Levitra and contact a doctor, pharmacist, or other healthcare professional right away.

    These are not all the side effects of Vardenafil (Levitra) tablets. For more information, ask your physician or pharmacist.


    How should Levitra be stored?

  • Store Levitra (Vardenafil Hydrochloride) tablets at room temperature between 59° and 86° F (15° to 30° C).
  • Keep this drug and all medicines out of the reach of children.


    General information about levitra.

    Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. Do not use Vardenafil HCl (Levitra) for a condition for which it was not prescribed. Do not give this medicine to other people, even if they have the same symptoms that you have. It may harm them.

    This leaflet summarizes the most important information about Levitra. If you would like more information, talk with your healthcare provider. You can ask your doctor or pharmacist for information about Levitra (Vardenafil Hydrochloride) that is written for health professionals.


    What are the ingredients of Levitra?

    Active Ingredient: vardenafil hydrochloride

    Inactive Ingredients: crospovidone, microcrystalline cellulose, colloidal silicon dioxide, hypromellose, magnesium stearate, polyethylene glycol, titanium dioxide, yellow ferric oxide, and red ferric oxide.

    Manufactured and distributed by Bayer, GlaxoSmithKline, Schering-Plough pharmaceutical companies and their divisions.

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